When a big city has a mysterious outbreak of blindness, the victims are quarantined by the government in a hospital without any medical care, treatment or hygiene. Among the first people affected by the so called “white blindness” are an ophthalmologist and his reluctant health wife that has not lost her sight but stays with him to help him in the difficult moment. The place immediately crowds and a group of criminals takes the power, demanding jewels and electronics first and sex later for the limited ratio of food they control.

The year is 2210. The universe is overrun with hundreds of vampire species that prey upon humans in brutal, surprise attacks. That’s when intergalactic Vampire Sanitation teams are called upon to lay waste to these vile predators. V-SAN crews, who’ve come to know their line of work as “the toughest job you’ll ever hate,” are comprised of rough and rugged men, women-and in the case of the Heironymous crew-a half human-half vampiress named Quintana (Natassia Malthe), who draws upon her psychic prowess to help the V-SANs track their quarry. Led by Captain Nicholas Churchill (Joe Lando) and second-in-command Damian Underwood (Dominic Zamprogna), the Heironymous team becomes the target of a deadly trap that has a much deeper and darker purpose. Directed by their vile leader Muco (Michael Ironside), the vampires have no plans of living peaceably with humans…they want to rule the universe.